Elevated Ck-mb without Myocardial Infarction

ultiple etiological factors have to be considered when faced with isolated elevation of Creatine Kinase-MB (CK-MB), an isoenzyme of Creatine Kinase (CK) without any change in total CK or increase in Troponin. These factors must be kept in mind before diagnosing a patient with acute coronary syndrome (ACS) and subjecting them to further investigation and therapy which could involve anticoagulation, exposing patients to risk of bleeding and invasive procedures which have their own inherent risk. We present a case of a patient with atypical chest pain who was found to have elevated CK-MB but with normal total CK and Troponin levels.